Gene information
Official symbol IGFBP1
Official full name insulin like growth factor binding protein 1
Gene type protein-coding gene
Chromosome7p12.3
Alias symbolIGF-BP25; AFBP; hIGFBP-1; PP12
Previous symbolIBP1
Gene familyInsulin like growth factor binding proteins
Resources
Entrez Gene 3484
HGNC HGNC:5469
Ensembl ENSG00000146678
Vega OTTHUMG00000152343
UCSC uc003tnp.4
GO terms: 30 records
GO Description Category LogP Number of genes Detail
GO:0001558 regulation of cell growth GO Biological Processes -19.1123936 65 More
GO:0005520 insulin-like growth factor binding GO Molecular Functions -5.13373504 7 More
GO:0005788 endoplasmic reticulum lumen GO Cellular Components -47.2996164 57 More
GO:0007167 enzyme-linked receptor protein signaling pathway GO Biological Processes -26.8285253 93 More
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway GO Biological Processes -16.7048742 60 More
GO:0007568 aging GO Biological Processes -23.5429582 29 More
GO:0008286 insulin receptor signaling pathway GO Biological Processes -3.0699689 9 More
GO:0009725 response to hormone GO Biological Processes -49.1091700 138 More
GO:0019838 growth factor binding GO Molecular Functions -18.6841278 23 More
GO:0030111 regulation of Wnt signaling pathway GO Biological Processes -7.94227486 39 More
GO:0030178 negative regulation of Wnt signaling pathway GO Biological Processes -7.69726068 26 More
GO:0030307 positive regulation of cell growth GO Biological Processes -13.7154299 34 More
GO:0031099 regeneration GO Biological Processes -17.4553316 23 More
GO:0032868 response to insulin GO Biological Processes -11.6850377 35 More
GO:0032869 cellular response to insulin stimulus GO Biological Processes -9.16399556 26 More
GO:0032870 cellular response to hormone stimulus GO Biological Processes -24.7707938 79 More
GO:0040007 growth GO Biological Processes -14.0580178 53 More
GO:0040008 regulation of growth GO Biological Processes -30.7609323 104 More
GO:0042246 tissue regeneration GO Biological Processes -5.28671514 12 More
GO:0043434 response to peptide hormone GO Biological Processes -26.1739008 69 More
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway GO Biological Processes -9.31062473 8 More
GO:0045927 positive regulation of growth GO Biological Processes -20.3035639 52 More
GO:0048589 developmental growth GO Biological Processes -14.0580178 53 More
GO:0060828 regulation of canonical Wnt signaling pathway GO Biological Processes -5.69122875 29 More
GO:0071375 cellular response to peptide hormone stimulus GO Biological Processes -15.9961580 44 More
GO:0071417 cellular response to organonitrogen compound GO Biological Processes -26.3253267 90 More
GO:0090090 negative regulation of canonical Wnt signaling pathway GO Biological Processes -6.26985667 21 More
GO:1901652 response to peptide GO Biological Processes -34.9047734 89 More
GO:1901653 cellular response to peptide GO Biological Processes -21.5212108 58 More
GO:1901699 cellular response to nitrogen compound GO Biological Processes -26.9091664 96 More
Drug-Gene interaction
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Related drugs: 9 records
Related studies: 4 records
Molecular factor Omics type Application Objective MI type Reference
insulin-like growth factor-binding protein 1 proteomics cardiovascular death[prognosis (bad)] acute myocardial infarction Wallander M et al. Diabetes Care. 2007
insulin-like growth factor-binding protein 1 proteomics death[prognosis (bad)] acute myocardial infarction Janszky I et al. Int J Cardiol. 2010
insulin-like growth factor-binding protein 1 proteomics heart failure[prognosis (bad)] acute myocardial infarction Janszky I et al. Int J Cardiol. 2010
insulin-like growth factor-binding protein 1 proteomics death[prognosis (bad)] acute myocardial infarction Ritsinger V et al. Diab Vasc Dis Res. 2018
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